2016 Mercedes-Benz S-Class Sedan Hybrid is the newer version with just one noteworthy difference, the fuel economy.. And finally, you get 6 more mpg with the 2015 Mercedes-Benz S-Class Sedan Hybrid than with the 2016 Mercedes-Benz S-Class Sedan Hybrid. Among similarities are the body structure, powertrain, market segment, starting price, horsepower, ground shadow size, height, and maximum occupancy.