Two Sedans with more similarities, such as the body structure, market segment, ground shadow size, height, and maximum occupancy, than differences, like the modifications, starting price, horsepower, and fuel economy. First of all, there is a $16,160 difference in the base MSRP. The 2015 Mercedes-Benz E-Class Sedan E 63 AMG 4MATIC S-Model has a higher starting price than the 2016 Lexus GS F. Also, the 2015 E-Class Sedan E 63 AMG 4MATIC S-Model has bigger and thirstier engine; the 2016 GS F gets 1 more mpg. Among similarities are the body structure, market segment, ground shadow size, height, and maximum occupancy.