Two Sedans with some similarities, but otherwise different in most aspects such as the powertrain, fuel economy, market segment, starting price, horsepower, and maximum occupancy. First of all, although the 2017 Acura RLX Hybrid has a more powerful engine than the 2017 Mercedes-Benz CLS-Class, it gets 7.3 more mpg. Also, there is a $7,600 difference in the base MSRP. The 2017 CLS-Class has a higher starting price than the 2017 RLX Hybrid. In addition, you'll seat one more passenger in the RLX Hybrid than in the CLS-Class. Among similarities are the body structure, market segment, ground shadow size, and height.